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| The Origins of Genome Architecture | 
 enlarge | List Price: $62.95
Buy New: $56.65
You Save: $6.30 (10%)
Buy New/Used from $56.65
Avg. Customer Rating:   (based on 1 reviews)
Sales Rank: 109994
Category: Book
Author: Michael Lynch
Publisher: Sinauer Associates Inc
Studio: Sinauer Associates Inc
Manufacturer: Sinauer Associates Inc
Label: Sinauer Associates Inc
Languages: English (Original Language), English (Unknown), English (Published)
Media: Hardcover
Edition: 1
Number Of Items: 1
Pages: 340
Shipping Weight (lbs): 2.7
Dimensions (in): 9.4 x 7.2 x 1.2
ISBN: 0878934847
Dewey Decimal Number: 572.838
EAN: 9780878934843
ASIN: 0878934847
Publication Date: March 30, 2007
Shipping: Eligible for Super Saver Shipping
Availability: Usually ships in 24 hours
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Product Description
With official genomic blueprints now available for hundreds of species, and thousands more expected in the near future, the field of biology has been forever transformed. Such readily accessible data have encouraged the proliferation of adaptive arguments for the evolution of gene and genomic features, often with little or no attention being given to simpler and more powerful alternative explanations. By integrating the central observations from molecular biology and population genetics relevant to comparative genomics, Lynch shows why the details matter. Presented in a nontechnical fashion, at both the population-genetic and molecular-genetic levels, this book offers a unifying explanatory framework for how the peculiar architectural diversity of eukaryotic genomes and genes came to arise. Under Lynch's hypothesis, the genome-wide repatterning of eukaryotic gene structure, which resulted primarily from nonadaptive processes, provided an entirely novel resource from which natural selection could secondarily build new forms of organismal complexity.
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| Customer Reviews:
Original view on evolution August 13, 2007
7 out of 15 found this review helpful
This book offers a non-conventional view on biological evolution, particularly that of animals, including humans. Solid molecular and population genetic analysis reveal that evolution of higher eukaryotes are realised predominantly by genetic drift of pseudo neutral mutations rather than by Darwinian type selection mechanisms. Authors' concept also might be applied to explain so far less discussed issue on the direction of evolution - from primitive forms towards more developed organisms.
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